The central nervous system, or CNS, comprises the brain, the spinal cord, and associated membranes. Under some circumstances, bacteria may enter areas of the CNS and cause CNS infections.
Shunt infections are often the result of contamination of proximal end of the shunt with normal skin flora. Shunt infection is usually caused by a person’s own bacterial organisms and isn’t acquired from other children or adults who are ill. This type of infection is most likely seen one to three months after surgery, but can occur up to six months after the placement of a shunt.
A shunt system can also be placed in the lumbar space of the spine and have the CSF redirected to the peritoneal cavity (Lumbar-peritoneal shunt).
Epidural abscess is a collection of pus between the dura mater and skull/Bone. Symptoms of epidural abscess include fever, headache, vomiting, and sometimes lethargy, focal neurologic deficits, seizures, and/or coma.
Ceftriaxone plus vancomycin is recommended fo CNS infections. Initial empiric antibiotics include ceftriaxone 2 g IV q 12 h; ceftriaxone is effective against streptococci, Enterobacteriaceae, and most anaerobes but not against Bacteroides fragilis. If S. aureus is at all suspected, vancomycin 1 g q 12 h is used with ceftriaxone.
Vancoplus offers following benefits in Meningitis & CNS infections:-
- Synergistic action
- Decreases the virulence of bacteria
- Safe with lesser toxicity
- Broad spectrum coverage
- Minimize the chances of resistance
- Excellent clinical & bacteriological cure rate
- Reduces hospitalization
- Empiric therapy for meningitis and CNS infections
- More than 115000 patients treated so far
- Patented world wide