In the case of over dosage of Vancoplus, nausea, vomiting, diarrhoea can occur. Supportive care is advised, with maintenance of glomerular filtration. Ceftriaxone and vancomycin are poorly removed from the blood by hemodialysis or peritoneal dialysis. Haemoperfusion with Amberlite resin XAD-4 has been reported to be of limited benefit for vancomycin removal. Hemofiltration effectively removes vancomycin from the blood.